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1

The discovery of α1-antitrypsin and its role in health and disease

Sabina M. Janciauskiene, Robert Bals, Rembert Koczulla, Claus Vogelmeier, Thomas Köhnlein, Tobias Welte

Journal:

Respiratory Medicine

Year:

2011

Language:

english

File:

PDF, 587 KB

english, 2011

2

Atorvastatin Reduces Plasma Levels of Chemokine (CXCL10) in Patients with Crohn's Disease

Grip, Olof, Janciauskiene, Sabina, Timmer, Antje

Journal:

Year:

2009

Language:

english

File:

PDF, 134 KB

english, 2009

3

Advances in Identifying Urine/Serum Biomarkers in Alpha-1 Antitrypsin Deficiency for More Personalized Future Treatment Strategies

Ferrarotti, Ilaria, Corsico, Angelo Guido, Stolk, Jan, Ottaviani, Stefania, Fumagalli, Marco, Janciauskiene, Sabina, Iadarola, Paolo

Journal:

COPD Journal of Chronic Obstructive Pulmonary Disease

Year:

2016

Language:

english

File:

PDF, 723 KB

english, 2016

4

Heme as a Target for Therapeutic Interventions

Immenschuh, Stephan, Vijayan, Vijith, Janciauskiene, Sabina, Gueler, Faikah

Journal:

Frontiers in Pharmacology

Year:

2017

Language:

english

File:

PDF, 1.18 MB

english, 2017

5

Sera from anti–Jo-1–positive patients with polymyositis and interstitial lung disease induce expression of intercellular adhesion molecule 1 in human lung endothelial cells

Sevim Barbasso Helmers, Pernilla Englund, Marianne Engström, Erik Åhlin, Maryam Fathi, Sabina Janciauskiene, Mikael Heimbürger, Johan Rönnelid, Ingrid E. Lundberg

Journal:

Arthritis & Rheumatism

Year:

2009

Language:

english

File:

PDF, 138 KB

english, 2009

6

N-glycosylation and biological activity of recombinant human alpha1-antitrypsin expressed in a novel human neuronal cell line

Véronique Blanchard, Xi Liu, Susann Eigel, Matthias Kaup, Silke Rieck, Sabina Janciauskiene, Volker Sandig, Uwe Marx, Peter Walden, Rudolf Tauber, Markus Berger

Journal:

Biotechnology and Bioengineering

Year:

2011

Language:

english

File:

PDF, 747 KB

english, 2011

7

Binding and uptake of Aβ1-42 by primary human astrocytes in vitro

Henrietta M. Nielsen, Robert Veerhuis, Bo Holmqvist, Sabina Janciauskiene

Journal:

Year:

2009

Language:

english

File:

PDF, 532 KB

english, 2009

8

Differential detection of PAS-positive inclusions formed by the Z, Siiyama, and Mmalton variants of α1-antitrypsin

Sabina Janciauskiene, Sten Eriksson, Francesco Callea, Meera Mallya, Aiwu Zhou, Kuniaki Seyama, Satoru Hata, David A. Lomas

Journal:

Year:

2004

Language:

english

File:

PDF, 591 KB

english, 2004

9

Effects of fibrillar C-terminal fragment of cleaved α1-antitrypsin on cholesterol homeostasis in HepG2 cells

Sabina Janciauskiene, Stefan Lindgren

Journal:

Year:

1999

Language:

english

File:

PDF, 251 KB

english, 1999

10

α1-Antitrypsin inhibits Moraxella catarrhalis MID protein-induced tonsillar B cell proliferation and IL-6 release

Radinka Hadzic, Izabela Nita, Helena Tassidis, Kristian Riesbeck, Anette Gjörloff Wingren, Sabina Janciauskiene

Journal:

Immunology Letters

Year:

2006

Language:

english

File:

PDF, 230 KB

english, 2006

11

Alzheimer’s peptide: A possible link between glaucoma, exfoliation syndrome and Alzheimer’s disease

Sabina Janciauskiene, Torsten Krakau

Journal:

Acta Ophthalmologica (Blackwell)

Year:

2001

Language:

english

File:

PDF, 38 KB

english, 2001

12

Human monocyte activation by cleaved form of alpha-1-antitrypsin : Involvement of the phagocytic pathway

Sabina Janciauskiene, Stefan Lindgren

Journal:

Year:

1999

Language:

english

File:

PDF, 531 KB

english, 1999

13

Concentration-dependent effects of native and polymerised α1-antitrypsin on primary human monocytes,in vitro

Ruta Aldonyte, Lennart Jansson, Sabina Janciauskiene

Journal:

BMC Cell Biology

Year:

2004

Language:

english

File:

PDF, 448 KB

english, 2004

14

Antibodies against gonadotropin-releasing hormone (GnRH) and destruction of enteric neurons in 3 patients suffering from gastrointestinal dysfunction

Bodil Ohlsson, Eva Ekblad, Béla Veress, Agneta Montgomery, Sabina Janciauskiene

Journal:

BMC Gastroenterology

Year:

2010

Language:

english

File:

PDF, 718 KB

english, 2010

15

Lymphocyte and monocyte flow cytometry immunophenotyping as a diagnostic tool in uncharacteristic inflammatory disorders

Helena Janols, Anders Bredberg, Irene Thuvesson, Sabina Janciauskiene, Olof Grip, Marlene Wullt

Journal:

BMC Infectious Diseases

Year:

2010

Language:

english

File:

PDF, 595 KB

english, 2010

16

Plasma levels of alpha1-antichymotrypsin and secretory leukocyte proteinase inhibitor in healthy and chronic obstructive pulmonary disease (COPD) subjects with and without severe α1-antitrypsin deficiency

Camilla Hollander, Ulla Westin, Anders Wallmark, Eeva Piitulainen, Tomas Sveger, Sabina M Janciauskiene

Journal:

BMC Pulmonary Medicine

Year:

2007

Language:

english

File:

PDF, 498 KB

english, 2007

17

Human mast cells decrease SLPI levels in type II – like alveolar cell model,in vitro

Camilla Hollander, Max Nyström, Sabina Janciauskiene, Ulla Westin

Journal:

Cancer Cell International

Year:

2003

Language:

english

File:

PDF, 684 KB

english, 2003

18

α1-antitrypsin and its C-terminal fragment attenuate effects of degranulated neutrophil-conditioned medium on lung cancer HCC cells,in vitro

Inga Zelvyte, Tim Stevens, Ulla Westin, Sabina Janciauskiene

Journal:

Cancer Cell International

Year:

2004

Language:

english

File:

PDF, 1.63 MB

english, 2004

19

Effects of alpha 1-antitrypsin on endotoxin-induced lung inflammation in

Devipriya Subramaniyam, Chad Steele, Thomas Köhnlein, Tobias Welte, Olof Grip, Sadis Matalon, Sabina Janciauskiene

Journal:

Inflammation Research

Year:

2010

Language:

english

File:

PDF, 247 KB

english, 2010

20

Low plasma levels of monocyte chemoattractant protein-1 (MCP-1), tumor necrosis factor-alpha (TNFα), and vascular endothelial growth factor (VEGF) in patients with alpha1-antitrypsin deficiency-related fibromyalgia

Ignacio Blanco, Sabina Janciauskiene, Izabela Nita, Enrique Fernández-Bustillo, Victoriano Cárcaba, César Gallo, Marlene Álvarez-Rico, Frederick de Serres, Nana Béridze

Journal:

Clinical Rheumatology

Year:

2010

Language:

english

File:

PDF, 183 KB

english, 2010

21

Abnormal overexpression of mastocytes in skin biopsies of fibromyalgia patients

Ignacio Blanco, Nana Béritze, Mario Argüelles, Victoriano Cárcaba, Fernando Fernández, Sabina Janciauskiene, Katerina Oikonomopoulou, Frederick J. de Serres, Enrique Fernández-Bustillo, Morley D. Holl

Journal:

Clinical Rheumatology

Year:

2010

Language:

english

File:

PDF, 403 KB

english, 2010

22

Secretory leukocyte protease inhibitor inhibits neutrophil apoptosis

Devipriya SUBRAMANIYAM, Camilla HOLLANDER, Ulla WESTIN, Jonas ERJEFÄLT, Tim STEVENS, Sabina JANCIAUSKIENE

Journal:

Year:

2011

Language:

english

File:

PDF, 393 KB

english, 2011

23

Clinical utility gene card for: α-1-antitrypsin deficiency

Janciauskiene, Sabina, Ferrarotti, Ilaria, Laenger, Florian, Jonigk, Danny, Luisetti, Maurizio

Journal:

European Journal of Human Genetics

Year:

2011

Language:

english

File:

PDF, 168 KB

english, 2011

24

A specific structural interaction of Alzheimer's peptide Aβ1–42 with α1-antichymotrypsin

Janciauskiene, Sabina, Eriksson, Sten, Wright, H. Tonie

Journal:

Natural Structural Biology

Year:

1996

File:

PDF, 545 KB

1996

25

Circulating monocytes and plasma inflammatory biomarkers in active Crohn's disease. Elevated oxidized low-density lipoprotein and the anti-inflammatory effect of atorvastatin

Olof Grip, Sabina Janciauskiene, Stefan Lindgren

Journal:

Inflammatory Bowel Diseases

Year:

2004

Language:

english

File:

PDF, 210 KB

english, 2004

26

Alzheimer's peptide and serine proteinase inhibitors in glaucoma and exfoliation syndrome

Sabina Janciauskiene, Torsten Krakau

Journal:

Documenta Ophthalmologica

Year:

2003

Language:

english

File:

PDF, 300 KB

english, 2003

27

239: Preeclampsia is a disease characterized by specific supramolecular aggregates of misfolded proteins and congophilia

Irina A. Buhimschi, Guomao Zhao, Margaret A. Baumbusch, Sabina Janciauskiene, Catalin S. Buhimschi

Journal:

American Journal of Obstetrics and Gynecology

Year:

2008

Language:

english

File:

PDF, 56 KB

english, 2008

28

Soluble adhesion molecules and angiotensin-converting enzyme in dementia

Henrietta M. Nielsen, Elisabet Londos, Lennart Minthon, Sabina M. Janciauskiene

Journal:

Neurobiology of Disease

Year:

2007

Language:

english

File:

PDF, 423 KB

english, 2007

29

Augmentation therapy in emphysema patient with ZZ α-1-antitrypsin deficiency

Caroline S. Sandström, Eeva Piitulainen, Sabina Janciauskiene

Journal:

Respiratory Medicine CME

Year:

2008

Language:

english

File:

PDF, 539 KB

english, 2008

30

Pravastatin down-regulates inflammatory mediators in human monocytes in vitro

Olof Grip, Sabina Janciauskiene, Stefan Lindgren

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 867 KB

english, 2000

31

Effects of native and cleaved forms of α1-antitrypsin on ME 1477 tumor cell functional activity

Inga Zelvyte, Hans-Olov Sjögren, Sabina Janciauskiene

Journal:

Cancer Detection and Prevention

Year:

2002

Language:

english

File:

PDF, 366 KB

english, 2002

32

The C-terminal peptide of α-1-antitrypsin increases low density lipoprotein binding in HepG2 cells

Sabina Janciauskiene, Stefan Lindgren, H. Tonie Wright

Journal:

Year:

1998

Language:

english

File:

PDF, 768 KB

english, 1998

33

Thein VitroEffect of Lithocholic Acid on the Polymerization Properties of PiZ Alpha-1-Antitrypsin

Marie-Christine Gerbod, Sabina Janciauskiene, Jan-Olof Jeppsson, Sten Eriksson

Journal:

Archives of Biochemistry and Biophysics

Year:

1998

Language:

english

File:

PDF, 202 KB

english, 1998

34

Effects of Noninhibitory α-1-Antitrypsin on Primary Human Monocyte Activation in Vitro

Fabian Moraga, Stefan Lindgren, Sabina Janciauskiene

Journal:

Archives of Biochemistry and Biophysics

Year:

2001

Language:

english

File:

PDF, 74 KB

english, 2001

35

B Cell Granule Peptides Affect Human Islet Amyloid Polypeptide (IAPP) Fibril Formationin Vitro

Sabina Janciauskiene, Sten Eriksson, Eric Carlemalm, Bo Ahrén

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 716 KB

english, 1997

36

Different Sensitivity to the Cytotoxic Action of IAPP Fibrils in Two Insulin-Producing Cell Lines, HIT-T15 and RINm5F Cells

Sabina Janciauskiene, Bo Ahrén

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 151 KB

english, 1998

37

In vitro complex formation between cholesterol and α1-proteinase inhibitor

Sabina Janciauskiene, Sten Eriksson

Journal:

Year:

1993

Language:

english

File:

PDF, 474 KB

english, 1993

38

Conformational changes of the α1-proteinase inhibitor affecting its cholesterol binding ability

Sabina Janciauskiene, Sten Eriksson

Journal:

Year:

1993

Language:

english

File:

PDF, 285 KB

english, 1993

39

The interaction of hydrophobic bile acids with the α1-proteinase inhibitor

Sabina Janciauskiene, Sten Eriksson

Journal:

Year:

1994

Language:

english

File:

PDF, 1.25 MB

english, 1994

40

Plexiform Lesions in Pulmonary Arterial Hypertension: Composition, Architecture, and Microenvironment

Danny Jonigk, Heiko Golpon, Clemens L. Bockmeyer, Lavinia Maegel, Marius M. Hoeper, Jens Gottlieb, Nils Nickel, Kais Hussein, Ulrich Maus, Ulrich Lehmann, Sabina Janciauskiene, Tobias Welte, Axel Have

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 3.86 MB

english, 2011

41

Divergent effects of α1-antitrypsin on neutrophil activation, in vitro

Sabina Janciauskiene, Inga Zelvyte, Lennart Jansson, Tim Stevens

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 334 KB

english, 2004

42

Inhibition of lipopolysaccharide-mediated human monocyte activation, in vitro, by α1-antitrypsin

Sabina Janciauskiene, Susanne Larsson, Peter Larsson, Robert Virtala, Lennart Jansson, Tim Stevens

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 523 KB

english, 2004

43

C-36 peptide, a degradation product of α1-antitrypsin, modulates human monocyte activation through LPS signaling pathways

Devipriya Subramaniyam, Pernilla Glader, Karin von Wachenfeldt, Jurate Burneckiene, Tim Stevens, Sabina Janciauskiene

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2006

Language:

english

File:

PDF, 689 KB

english, 2006

44

α1-Antitrypsin regulates CD14 expression and soluble CD14 levels in human monocytes in vitro

Izabela M. Nita, Danielius Serapinas, Sabina M. Janciauskiene

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2007

Language:

english

File:

PDF, 815 KB

english, 2007

45

TNF-α-induced self expression in human lung endothelial cells is inhibited by native and oxidized α1-antitrypsin

Devipriya Subramaniyam, Robert Virtala, Krzysztof Pawłowski, Ib Groth Clausen, S. Warkentin, Tim Stevens, Sabina Janciauskiene

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2008

Language:

english

File:

PDF, 1.01 MB

english, 2008

46

Macrophage responses to interferon-γ are dependent on cystatin C levels

Katarina H. Frendéus, Hanna Wallin, Sabina Janciauskiene, Magnus Abrahamson

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2009

Language:

english

File:

PDF, 819 KB

english, 2009

47

Cholesterol rich lipid raft microdomains are gateway for acute phase protein, SERPINA1

Devipriya Subramaniyam, Huiping Zhou, Min Liang, Tobias Welte, Ravi Mahadeva, Sabina Janciauskiene

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2010

Language:

english

File:

PDF, 654 KB

english, 2010

48

Secreted leukocyte protease inhibitor is present in aqueous humours from cataracts and other eye pathologies

Sabina Janciauskiene, Lars Brandt, Anders Wallmark, Ulla Westin, Torsten Krakau

Journal:

Experimental Eye Research

Year:

2006

Language:

english

File:

PDF, 152 KB

english, 2006

49

Plexiform vasculopathy of severe pulmonary arterial hypertension and microRNA expression

Clemens L. Bockmeyer, Lavinia Maegel, Sabina Janciauskiene, Johanna Rische, Ulrich Lehmann, Ulrich A. Maus, Nils Nickel, Axel Haverich, Marius M. Hoeper, Heiko A. Golpon, Hans Kreipe, Florian Laenger,

Journal:

The Journal of Heart and Lung Transplantation

Year:

2012

Language:

english

File:

PDF, 2.46 MB

english, 2012

50

Preventing and reversing the cellular consequences of Z alpha-1 antitrypsin accumulation by targeting s4A

Sam Alam, Jicun Wang, Sabina Janciauskiene, Ravi Mahadeva

Journal:

Journal of Hepatology

Year:

2012

Language:

english

File:

PDF, 1.21 MB

english, 2012